The TSC1 Monoclonal Antibody from Bioss Inc. is a Mouse Monoclonal antibody to TSC1. This antibody recognizes Human antigen. The TSC1 Monoclonal Antibody has been validated for the following applications: Western Blot.
Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling